The following ASP.NET controls are not compatible with partial-page updates, and are therefore not supported inside an UpdatePanel control:
1. TreeView and Menu controls.
2. Web Parts controls. For more information, see ASP.NET Web Parts Controls.
3. FileUpload controls when they are used to upload files as part of an asynchronous postback.
5. Login, PasswordRecovery, ChangePassword, and CreateUserWizard controls whose contents have not been converted to editable templates.
6. The Substitution control.
7. Validation controls, which includes the BaseCompareValidator, BaseValidator, CompareValidator, CustomValidator, RangeValidator, RegularExpressionValidator, RequiredFieldValidator, and ValidationSummary control.